Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) for PDB: 2XNP
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339800((+/-)-4-(5-(1-Methylpiperidin-4-yloxy)-1H-benzo[d]...)
Affinity DataIC50:  230nMAssay Description:Inhibition of NEK2 autophosphorylation preincubated with compound by DELFIA assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339801((R)-4-(5-(1-Methylpiperidin-4-yloxy)-1H-benzo[d]im...)
Affinity DataIC50:  360nMAssay Description:Inhibition of NEK2More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339800((+/-)-4-(5-(1-Methylpiperidin-4-yloxy)-1H-benzo[d]...)
Affinity DataIC50:  570nMAssay Description:Inhibition of NEK2More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339800((+/-)-4-(5-(1-Methylpiperidin-4-yloxy)-1H-benzo[d]...)
Affinity DataIC50:  910nMAssay Description:Inhibition of NEK2 assessed as inhibition of substrate phosphorylation preincubated for 5 mins before addition of substrate by DELFIA assayMore data for this Ligand-Target Pair