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Found 2 Enz. Inhib. hit(s) for PDB: 2ZO3
TargetProthrombin(Homo sapiens (Human))
Life Science R & D, Lgci

Curated by ChEMBL
LigandPNGBDBM50111104(2N-(4-Benzamidinemethyl)-1-[2-Amino-3,3-diphenyl-(...)
Affinity DataKi:  0.0360nMAssay Description:Binding affinity against human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Life Science R & D, Lgci

Curated by ChEMBL
LigandPNGBDBM32657(benzamidine- based compound, 6)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic inhibition of human thrombin was determined photometrically at 405 nm using the chromogenic substrate Pefachrom tPa. Reactions were performed...More data for this Ligand-Target Pair