Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 3B25
TargetHeat shock protein HSP 90-alpha(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50354826(CHEMBL1834091)
Affinity DataKd:  860nMAssay Description:Binding affinity to human HSP90alpha assessed as 2D1H-15N chemical shift perturbation by NMR spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50354826(CHEMBL1834091)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of human N-terminal GST-tagged HSP90alpha expressed in Escherichia coli after 1 hr using 10 mM of ATP and malachite green by microplate re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)