Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 3BLR
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The Council of Scientific & Industrial Research

US Patent
LigandPNGBDBM384357(US9932327, Compound Flavopiridol)
Affinity DataIC50: 20nMAssay Description:CDK-9/Cyclin T1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 1 mg/ml BSA, 0.1% mercaptoethanol) was assayed against a substrate peptide (YSPTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 9(Human)
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM384357(US9932327, Compound Flavopiridol)
Affinity DataIC50: 177nMAssay Description:Inhibition of CDK9 in human U2OS cells assessed as reduction in CTD phosphorylation at Ser2 residue measured after 16 hrs by propidium iodide stainin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)