Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 3CE0
LigandPNGBDBM27497(2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...)
Affinity DataKd:  700nMAssay Description:Binding affinity to human PARP3 PARP domain by isothermal titration colorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Health & Science University

Curated by ChEMBL
LigandPNGBDBM27497(2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of full length recombinant human His6-tagged PARP3 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Health & Science University

Curated by ChEMBL
LigandPNGBDBM27497(2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of full length recombinant human His6-tagged PARP3 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)