Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) for PDB: 3D5F
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  640nMAssay Description:Transactivation of GAL4-fused PPARbeta LBD expressed in HepG2 cells after 20 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataKd:  76nMAssay Description:Binding affinity to PPARdelta (unknown origin) assessed as thermodynamic dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  20nMAssay Description:Transactivation of GAL4-fused human PPARdelta LBD expressed in human HepG2 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataKon:  0.430M-1s-1Assay Description:Binding affinity to PPARdelta (unknown origin) assessed as kinetic dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  39nMAssay Description:Transactivation of human PPARdelta expressed in African green monkey COS7 cells incubated overnight by dual-glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human GAL4-PPARdelta ligand binding domain expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human GAL4-fused PPARdelta ligand binding domain expressed in COS-1 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  39nMAssay Description:Transactivation of GAL4-fused human PPARdelta ligand binding domain transfected in african green monkey COS7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  650nMAssay Description:Transactivation of GAL4-fused PPARbeta (delta) ligand binding domain transfected in human HepG2 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at PPARdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  125nMAssay Description:Activity at PPARbeta/delta by luciferase reporter gene transactivation assay in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at yeast Gal4-fused human PPARdelta transfected in human HepG2 cells assessed as transactivation by measuring beta-galactosidase act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human PPAR-delta expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  210nMAssay Description:Transactivation of GAL4-tagged human PPARdelta LBD expressed in human HepG2 cells at 100 nM to 100 uM incubated for 20 to 22 hrs by luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  530nMAssay Description:Agonist activity for Human PPAR delta receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Mouse)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  3.80E+3nMAssay Description:Agonist activity for murine PPAR delta receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  61nMAssay Description:Agonist activity at PPARbeta (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataIC50: 13nMAssay Description:Agonist activity at GAL4 DNA-binding domain fused PPARdelta receptor (unknown origin) ligand binding domain expressed in UAS-bla HEK 293T cells asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)