Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) for PDB: 3FR0
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50248442(2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl...)
Affinity DataEC50:  420nMAssay Description:Activation of human glucokinase by glucose-6-phosphate dehydrogenase coupled continuous spectrophotometric assay in presence of 2.5 mM glucoseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50248442(2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl...)
Affinity DataEC50:  140nMAssay Description:Activation of human glucokinase by glucose-6-phosphate dehydrogenase coupled continuous spectrophotometric assay in presence of 10 mM glucoseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50248442(2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl...)
Affinity DataEC50:  420nMAssay Description:Activation of flag-tagged human recombinant liver glucokinase expressed in Escherichia coli by glucose-6-phosphate dehydrogenase coupled continuous s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50248442(2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl...)
Affinity DataEC50:  140nMAssay Description:Activation of flag-tagged human recombinant liver glucokinase expressed in Escherichia coli by glucose-6-phosphate dehydrogenase coupled continuous s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50248442(2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl...)
Affinity DataEC50:  420nMAssay Description:Activation of N-terminal His-tagged human recombinant liver glucokinase expressed in Escherichia coli BL21 (DE3) by glucose-6-phosphate dehydrogenase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50248442(2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl...)
Affinity DataEC50:  140nMAssay Description:Activation of N-terminal His-tagged human recombinant liver glucokinase expressed in Escherichia coli BL21 (DE3) by glucose-6-phosphate dehydrogenase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50248442(2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl...)
Affinity DataKd:  440nMAssay Description:Binding affinity to recombinant wild-type human pancreatic glucokinase expressed in Escherichia coli K-12 at 11 uM by isothermal titration calorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)