Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 3FV8
TargetMitogen-activated protein kinase 8(Human)
The Scripps Research Institute

LigandPNGBDBM32460(piperazine amide, 4g)
Affinity DataIC50: 140nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM32460(piperazine amide, 4g)
Affinity DataIC50: 160nMpH: 7.0 T: 2°CAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)