Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 3HRF
Target3-phosphoinositide-dependent protein kinase 1(Human)
Universit£Tsklinikum Frankfurt

Curated by ChEMBL
LigandPNGBDBM50296949(PS48 | (2Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoi...)
Affinity DataKd:  1.03E+4nMAssay Description:Binding affinity to human PDPK1 Y288G/Q292A mutant expressed in insect cell system assessed as substrate phosphorylation by isothermal titration calo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target3-phosphoinositide-dependent protein kinase 1(Human)
Universit£Tsklinikum Frankfurt

Curated by ChEMBL
LigandPNGBDBM50296949(PS48 | (2Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoi...)
Affinity DataKd:  1.03E+4nMAssay Description:Binding affinity to PDK1 (50 to 359) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target3-phosphoinositide-dependent protein kinase 1(Human)
Universit£Tsklinikum Frankfurt

Curated by ChEMBL
LigandPNGBDBM50296949(PS48 | (2Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoi...)
Affinity DataIC50: 9.70E+4nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen Assay (Perkin Elmer) was performed according to the manufacturer's protocol in 384-well microtiter plates. Incubations were performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)