Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) for PDB: 3IPS
TargetOxysterols receptor LXR-alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126018({3-chloro-4-[(3-{[7-propyl-3-(trifluoromethyl)-1,2...)
Affinity DataEC50:  5.90E+3nMAssay Description:Activity at LXR alpha as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126018({3-chloro-4-[(3-{[7-propyl-3-(trifluoromethyl)-1,2...)
Affinity DataEC50:  35nMAssay Description:Effective concentration for cofactor association with recombinant liver X receptor-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126018({3-chloro-4-[(3-{[7-propyl-3-(trifluoromethyl)-1,2...)
Affinity DataEC50:  1.79E+3nMAssay Description:Effective concentration against liver X receptor-alpha in HEK293 cell transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126018({3-chloro-4-[(3-{[7-propyl-3-(trifluoromethyl)-1,2...)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human recombinant LXRalpha expressed in Escherichia coli BL21 cells assessed as association of recombinant SRC1 to LXRalpha ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126018({3-chloro-4-[(3-{[7-propyl-3-(trifluoromethyl)-1,2...)
Affinity DataEC50:  35nMAssay Description:Effective concentration for cofactor association with recombinant liver X receptor-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126018({3-chloro-4-[(3-{[7-propyl-3-(trifluoromethyl)-1,2...)
Affinity DataIC50: 32nMAssay Description:Activity at LXR alpha as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126018({3-chloro-4-[(3-{[7-propyl-3-(trifluoromethyl)-1,2...)
Affinity DataIC50: 35nMAssay Description:Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-alpha in SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)