Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 3KCF
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50304855(4-(3-(methoxymethyl)phenyl)-1,2-dimethyl-5-(quinox...)
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50304855(4-(3-(methoxymethyl)phenyl)-1,2-dimethyl-5-(quinox...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)