Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 3KKU
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322742BDBM50322742(N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenox...)
Affinity DataIC50: 800nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322742BDBM50322742(N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenox...)
Affinity DataIC50: 800nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine expressed in Escherichia coli SG13009 using Z-FR-AMC as substrate after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322742BDBM50322742(N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenox...)
Affinity DataIC50: 800nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322742BDBM50322742(N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenox...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain assessed as Z-Phe-Arg-aminomethylcoumarin cleavage by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322742BDBM50322742(N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenox...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)