Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 3ME3
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361557BDBM50361557(CHEMBL1089334)
Affinity DataEC50:  30nMAssay Description:Activation of PKM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361557BDBM50361557(CHEMBL1089334)
Affinity DataEC50:  38nMAssay Description:Activation of human PKM2 assessed as ATP product formation after 1 hr by luminescent pyruvate kinase-luciferase coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361557BDBM50361557(CHEMBL1089334)
Affinity DataEC50:  38nMAssay Description:Activation of human recombinant full length His-tagged PKM2 (Asp354, Lys311, Glu397, Gly315 residues)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361557BDBM50361557(CHEMBL1089334)
Affinity DataEC50:  38nMAssay Description:Activation of PKM2 (unknown origin) Asp354, Phe26, Lys311 residuesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)