Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 3P8H
TargetIsoform 4 of Lethal(3)malignant brain tumor-like protein 1 (4)(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341828BDBM50341828(3-bromo-5-[(4-pyrrolidin-1-ylpiperidin-1-yl)carbon...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of L3MBTL1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIsoform 4 of Lethal(3)malignant brain tumor-like protein 1 (4)(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341828BDBM50341828(3-bromo-5-[(4-pyrrolidin-1-ylpiperidin-1-yl)carbon...)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to human L3MBTL1 assessed as dissociation constant by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIsoform 4 of Lethal(3)malignant brain tumor-like protein 1 (4)(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341828BDBM50341828(3-bromo-5-[(4-pyrrolidin-1-ylpiperidin-1-yl)carbon...)
Affinity DataIC50: 6.00E+3nMAssay Description:Binding affinity to human L3MBTL1 by chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIsoform 4 of Lethal(3)malignant brain tumor-like protein 1 (4)(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341828BDBM50341828(3-bromo-5-[(4-pyrrolidin-1-ylpiperidin-1-yl)carbon...)
Affinity DataKd:  1.00E+4nMAssay Description:Displacement of FAM-AHA-ARTKQTARK(Me)STGGKA-CO2H from human L3MBTL1 assessed as apparent dissociation constant after 20 mins by FP-displacement AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLethal(3)malignant brain tumor-like protein 1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341828BDBM50341828(3-bromo-5-[(4-pyrrolidin-1-ylpiperidin-1-yl)carbon...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of His-tagged L3MBTL1 (unknown origin) using H4K20Me1 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)