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Found
1
Enz. Inhib. hit(s) for PDB:
3QC4
Target
3-phosphoinositide-dependent protein kinase 1
(Human)
Merck Research Laboratories
Ligand
BDBM92406
(PDK1 inhibitor, 7)
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Affinity Data
EC50: 1nM
Assay Description:
Enzyme potency (PDK1 EC50)was determined using recombinant, purified full-length human PDK1 enzyme and AKT-Thr-308-tide as substrate.
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Target Info
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Ligand Info
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PC cid
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In Depth
Date in BDB:
8/27/2012
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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