TargetReceptor tyrosine-protein kinase erbB-2(Human)
Korea University of Science and Technology (Ust)
Curated by ChEMBL
Korea University of Science and Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of HER2 (unknown origin) after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Korea University of Science and Technology (Ust)
Curated by ChEMBL
Korea University of Science and Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 9.10nMAssay Description:Inhibition of C-terminal His6-tagged HER2 (703 to 1029 residues) (unknown origin) expressed in Sf9 insect cells using TK as substrate preincubated fo...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Korea University of Science and Technology (Ust)
Curated by ChEMBL
Korea University of Science and Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human N-terminus peptide (DYKDDDD)-tagged HER2 expressed in baculovirus infected insect cells using [gamma-32P]ATP as substrate after 6...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Korea University of Science and Technology (Ust)
Curated by ChEMBL
Korea University of Science and Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human N-terminal DYKDDDD-tagged HER2 cytoplasmic domain (676 to 1255) expressed in baculovirus expression system incubated for 5 mins p...More data for this Ligand-Target Pair

3D Structure (crystal)