Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 3SFH
TargetHistone deacetylase 8(Human)
Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350236(CHEMBL1812335)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant HDAC 8 by HDAC-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Human)
Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350236(CHEMBL1812335)
Affinity DataIC50: 90nMAssay Description:Inhibition of N terminal hexahistidine-tagged human HDAC8 expressed in Sf9 cells after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Human)
Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350236(CHEMBL1812335)
Affinity DataIC50: 210nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Human)
Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350236(CHEMBL1812335)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of human KDAC8 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)