Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) for PDB: 3SMR
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50428254(CHEMBL1609857)
Affinity DataKd:  7.00E+3nMAssay Description:Displacement of N-terminal FITC-labeled GSARAEVHLRKS from WDR5 (1 to 334 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50428254(CHEMBL1609857)
Affinity DataKd:  1.20E+4nMAssay Description:Displacement of GSARAEVHLRKS from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50428254(CHEMBL1609857)
Affinity DataKd:  7.00E+3nMAssay Description:Binding affinity to WDR5 (unknown origin) using GSARAEVHLRKS peptide substrate by fluorescence polarization assaysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50428254(CHEMBL1609857)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity to human WDR5 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50428254(CHEMBL1609857)
Affinity DataKd:  6.90E+3nMAssay Description:Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50428254(CHEMBL1609857)
Affinity DataKd:  7.00E+3nMAssay Description:Displacement of MLL-WIN N-terminal FITC-tagged GSARAEVHLRKS peptide from human WDR5 (1-334) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)