Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 3TWD
TargetBifunctional protein GlmU(Escherichia coli (strain K12))
Astrazeneca

LigandPNGBDBM92472(Sulfonamide, 3)
Affinity DataIC50: 18nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional protein GlmU(Escherichia coli (strain K12))
Astrazeneca

LigandPNGBDBM92472(Sulfonamide, 3)
Affinity DataIC50: 20nMAssay Description:Inhibition of Escherichia coli GlmU acetyltransferase activity assessed as coenzyme A production using acetyl CoA substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional protein GlmU(Escherichia coli (strain K12))
Astrazeneca

LigandPNGBDBM92472(Sulfonamide, 3)
Affinity DataIC50: 20nMAssay Description:Inhibition of Escherichia coli GlmU acetyltransferase activity assessed as coenzyme A production using acetyl CoA substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)