Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 4DCH
TargetHexokinase-4(Human)
Florida State University

Curated by ChEMBL
LigandPNGBDBM50346020((2R)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-t...)
Affinity DataKd:  500nMAssay Description:Binding affinity to recombinant wild-type human pancreatic glucokinase expressed in Escherichia coli K-12 by isothermal titration calorimetry in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHexokinase-4(Human)
Florida State University

Curated by ChEMBL
LigandPNGBDBM50346020((2R)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-t...)
Affinity DataEC50:  690nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHexokinase-4(Human)
Florida State University

Curated by ChEMBL
LigandPNGBDBM50346020((2R)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-t...)
Affinity DataEC50:  500nMAssay Description:Activation of glucokinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)