Found 10 Enz. Inhib. hit(s) for PDB: 4DJH TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Antagonist activity at kappa opioid receptor (unknown origin) assessed as stimulation of [35S]GTPgammaSMore data for this Ligand-Target Pair
3D Structure (crystal)TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Displacement of [3H]U69,593 from kappa opioid receptor in guinea pig brain membranes after 2 hrsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Antagonist activity at kappa opioid receptor in guinea pig caudate assessed as inhibition of U69593-stimulated [35S]-GTP[gammaS] bindingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Displacement of [3H]diprenorphine from human recombinant mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.0591nMAssay Description:Displacement of [3H]diprenorphine from human opioid kappa receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.320nMAssay Description:Binding affinity of compound for Opioid receptor kappa 1 was determined using [3H]U-69593 as radioligand from guinea pig caudateMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.320nMAssay Description:Binding affinity towards human cloned Opioid receptor kappa 1 using [3H]U-69593More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.320nMAssay Description:Inhibition of [3H]U-69593 binding to Opioid receptor kappa 1 of guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 6nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
