Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 4DK7
TargetOxysterols receptor LXR-beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50179869(N-methyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluo...)
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRbeta by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50179869(N-methyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluo...)
Affinity DataEC50:  2.93E+3nMAssay Description:Agonist activity against human LXRbeta expressed in human HEK293T cells co-expressing CMX-GAL4N-hLXRbeta incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)