Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) for PDB: 9LDT
TargetL-lactate dehydrogenase A chain(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM23222(carbamoylformic acid | Oxalamic acid | Oxamidic Ac...)
Affinity DataIC50: 5.72E+4nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHA by UV endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetL-lactate dehydrogenase A chain(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM23222(carbamoylformic acid | Oxalamic acid | Oxamidic Ac...)
Affinity DataIC50: 5.72E+4nMAssay Description:Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate after 10 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetL-lactate dehydrogenase A chain(Mouse)
Instituto Politécnico Nacional

LigandPNGBDBM23222(carbamoylformic acid | Oxalamic acid | Oxamidic Ac...)
Affinity DataIC50: 8.00E+4nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetL-lactate dehydrogenase A chain(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM23222(carbamoylformic acid | Oxalamic acid | Oxamidic Ac...)
Affinity DataKi:  2.60E+4nMAssay Description:Inhibition of human LDH-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetL-lactate dehydrogenase A chain(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM23222(carbamoylformic acid | Oxalamic acid | Oxamidic Ac...)
Affinity DataKi:  1.36E+5nMAssay Description:Competitive inhibition of human LDH5 in presence of NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetL-lactate dehydrogenase A chain(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM23222(carbamoylformic acid | Oxalamic acid | Oxamidic Ac...)
Affinity DataKi:  1.38E+5nMAssay Description:Inhibition of human LDH-A using pyruvate as substrate and NADH as cofactor at 125 uM after 5 mins by calorimetric assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetL-lactate dehydrogenase A chain(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM23222(carbamoylformic acid | Oxalamic acid | Oxamidic Ac...)
Affinity DataKi:  1.38E+5nMAssay Description:Inhibition of human LDHA using pyruvate as substrate assessed as disappearance of NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)