The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.9M data for 1.2M Compounds and 9.3K Targets. Of those, 1,352K data for 627K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Advanced Search

20 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Recent Update on Human Lactate Dehydrogenase Enzyme 5 (hLDH5) Inhibitors: A Promising Approach for Cancer Chemotherapy.EBI
National Cancer Institute-Cro
An update on therapeutic opportunities offered by cancer glycolytic metabolism.EBI
Universit£
Optimization of 5-(2,6-dichlorophenyl)-3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase.EBI
Genentech
Identification of substituted 3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase.EBI
Genentech
Identification of 2-amino-5-aryl-pyrazines as inhibitors of human lactate dehydrogenase.EBI
Genentech
Identification of substituted 2-thio-6-oxo-1,6-dihydropyrimidines as inhibitors of human lactate dehydrogenase.EBI
Genentech
Structure-based optimization of hydroxylactam as potent, cell-active inhibitors of lactate dehydrogenase.EBI
Genentech
New salicylic acid derivatives, double inhibitors of glycolate oxidase and lactate dehydrogenase, as effective agents decreasing oxalate production.EBI
Universidad De Granada
Discovery of novel human lactate dehydrogenase inhibitors: Structure-based virtual screening studies and biological assessment.EBI
Sapienza University of Rome
Optimization of ether and aniline based inhibitors of lactate dehydrogenase.EBI
Vanderbilt University
Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice.EBI
Genentech
Interrogating the Lactate Dehydrogenase Tetramerization Site Using (Stapled) Peptides.EBI
Universit£
Selective inhibitors of human lactate dehydrogenases and lactate dehydrogenase from the malarial parasite Plasmodium falciparum.EBI
University of New Mexico School of Medicine
Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH).EBI
National Center For Advancing Translational Sciences
Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds.BDB
Helmholtz-Institute For Pharmaceutical Research Saarland