PMID

Data

Article Title

Organization

Pharmacophoric modifications lead to superpotentavß3 integrin ligands with suppresseda5ß1 activity.

Technische Universit£T M£Nchen

Biselectivity of isoDGR peptides for fibronectin binding integrin subtypesa5ß1 andavß6: conformational control through flanking amino acids.

Technische Universit£T M£Nchen

R-isomers of Arg-Gly-Asp (RGD) mimics as potent alphavbeta3 inhibitors.

Pfizer

Discovery of +(2-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid as potent and selective alphavbeta3 inhibitor: design, synthesis, and optimization.

Pfizer

Halting the Spread of Herpes Simplex Virus-1: The Discovery of an Effective Dual ?v?6/?v?8 Integrin Ligand.

Universit£

Synthesis of pyrazoles and isoxazoles as potent alpha(v)beta3 receptor antagonists.

Pfizer

Synthesis of 2,5-thiazole butanoic acids as potent and selective alpha(v)beta3 integrin receptor antagonists with improved oral pharmacokinetic properties.

Pfizer

Convergent, parallel synthesis of a series of beta-substituted 1,2,4-oxadiazole butanoic acids as potent and selective alpha(v)beta3 receptor antagonists.

Pfizer

SARS-CoV-2: Novel Therapeutic Approaches for Diagnosis and Treatment.

Usona Institute

Tuning the Biological Activity of RGD Peptides with Halotryptophans?.

Bielefeld University

Discovery of the first potent and selective ?

University of Strathclyde

Dual antagonists of ?5?1/?v?1 integrin for airway hyperresponsiveness.

University of California San Francisco

Nanomolar small molecule inhibitors for alphav(beta)6, alphav(beta)5, and alphav(beta)3 integrins.

Merck

New ?-Lactam Derivatives Modulate Cell Adhesion and Signaling Mediated by RGD-Binding and Leukocyte Integrins.

University of Bologna

Novel cilengitide-based cyclic RGD peptides as ?v?

Division of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Selective Targeting of Integrin ?v?8 by a Highly Active Cyclic Peptide.

Technische Universit£T M£Nchen

Profile of a Highly Selective Quaternized Pyrrolidine Betaine ?

Glaxosmithkline Medicines Research Centre

Discovery of an Orally Bioavailable Pan ?v Integrin Inhibitor for Idiopathic Pulmonary Fibrosis.

Glaxosmithkline Medicines Research Centre

Strategies to inhibit tumor associated integrin receptors: rationale for dual and multi-antagonists.

University of Bradford

Structure Activity Relationships of ?v Integrin Antagonists for Pulmonary Fibrosis by Variation in Aryl Substituents.

University of Nottingham

Discovery of ( S)-3-(3-(3,5-Dimethyl-1 H-pyrazol-1-yl)phenyl)-4-(( R)-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic Acid, a Nonpeptidic ?

University of Strathclyde