Binding Database

BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.8M data for 1.2M Compounds and 9.2K Targets. Of those, 1,346K data for 622K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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13 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

Optimization of spirocyclic proline tryptophan hydroxylase-1 inhibitors.

Karos Pharmaceuticals

Discovery of acyl guanidine tryptophan hydroxylase-1 inhibitors.

Karos Pharmaceuticals

Discovery of spirocyclic proline tryptophan hydroxylase-1 inhibitors.

Karos Pharmaceuticals

Tryptophan hydroxylase 1 (Tph-1)-targeted bone anabolic agents for osteoporosis.

Nanjing University

Substituted 3-(4-(1,3,5-triazin-2-yl)-phenyl)-2-aminopropanoic acids as novel tryptophan hydroxylase inhibitors.

Lexicon Pharmaceuticals

Modulation of peripheral serotonin levels by novel tryptophan hydroxylase inhibitors for the potential treatment of functional gastrointestinal disorders.

Lexicon Pharmaceuticals

Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors.

Leibniz-Forschungsinstitut F�R Molekulare Pharmakologie (Fmp)

Peripheral Selective Oxadiazolylphenyl Alanine Derivatives as Tryptophan Hydroxylase 1 Inhibitors for Obesity and Fatty Liver Disease.

Gwangju Institute of Science and Technology