PMID

Data

Article Title

Organization

Pyridine-3-carboxamide-6-yl-ureas as novel inhibitors of bacterial DNA gyrase: structure based design, synthesis, SAR and antimicrobial activity.

University of Leeds

Discovery of dual GyrB/ParE inhibitors active against Gram-negative bacteria.

Experimental Therapeutics Centre

Novel dual-targeting benzimidazole urea inhibitors of DNA gyrase and topoisomerase IV possessing potent antibacterial activity: intelligent design and evolution through the judicious use of structure-guided design and structure-activity relationships.

Vertex Pharmaceuticals