11 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors.
Infinity Pharmaceuticals
Synthesis of rocaglamide hydroxamates and related compounds as eukaryotic translation inhibitors: synthetic and biological studies.
Boston University
1-Aminomethyl SAR in a novel series of flavagline-inspired eIF4A inhibitors: Effects of amine substitution on cell potency and in vitro PK properties.
Effector Therapeutics
Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase.
Inception Therapeutics
Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A.
Mcgill University
Discovery of Novel 1,4-Diacylpiperazines as Selective and Cell-Active eIF4A3 Inhibitors.
Takeda Pharmaceutical
Discovery of spiro[indole-3,2'-pyrrolidin]-2(1H)-one based inhibitors targeting Brr2, a core component of the U5 snRNP.
Takeda Pharmaceutical
Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2.
Takeda California
