31 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Data
Article Title
Organization
Progress in the development of fatty acid synthase inhibitors as anticancer targets.
University of South Alabama
Fatty Acid Synthase (FASN) Inhibitors as Potential Treatment for Cancer, Obesity, and Liver Related Disorders.
Therachem Research Medilab (India)
Repositioning proton pump inhibitors as anticancer drugs by targeting the thioesterase domain of human fatty acid synthase.
Indiana University School of Medicine
Imidazopyridine-Based Fatty Acid Synthase Inhibitors That Show Anti-HCV Activity and in Vivo Target Modulation.
3-V Biosciences
Fatty acid synthase inhibitory activity of acylphloroglucinols isolated from Dryopteris crassirhizoma.
Korea Research Institute of Bioscience and Biotechnology
Structure-activity relationships at the 5-position of thiolactomycin: an intact (5R)-isoprene unit is required for activity against the condensing enzymes from Mycobacterium tuberculosis and Escherichia coli.
National Institute of Allergy and Infectious Diseases
Synthesis and evaluation of analogues of S-adenosyl-L-methionine, as inhibitors of the E. coli cyclopropane fatty acid synthase.
Universit£
Discovery of BI 99179, a potent and selective inhibitor of type I fatty acid synthase with central exposure.
Boehringer Ingelheim Pharma
Fatty acid synthase inhibitors of phenolic constituents isolated from Garcinia mangostana.
Chinese Academy of Sciences
3-Aryl-4-hydroxyquinolin-2(1H)-one derivatives as type I fatty acid synthase inhibitors.
Merck Research Laboratories
Therapeutic Activity of the Lansoprazole Metabolite 5-Hydroxy Lansoprazole Sulfide in Triple-Negative Breast Cancer by Inhibiting the Enoyl Reductase of Fatty Acid Synthase.
Indiana University School of Medicine
Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN).
Forma Therapeutics
Application of a flexible synthesis of (5R)-thiolactomycin to develop new inhibitors of type I fatty acid synthase.
Johns Hopkins University
Design and synthesis of a series of bioavailable fatty acid synthase (FASN) KR domain inhibitors for cancer therapy.
Janssen Research and Development
A strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids.
Baylor University
Dihalogenated sulfanilamides and benzolamides are effective inhibitors of the three ß-class carbonic anhydrases from Mycobacterium tuberculosis.
Universit?? Degli Studi Di Firenze
Quinazoline-urea, new protein kinase inhibitors in treatment of prostate cancer.
Universit?? Lille Nord De France
Trypanocidal bisbenzylisoquinoline alkaloids are inhibitors of trypanothione reductase.
Orstom
Design of mutation-resistant HIV protease inhibitors with the substrate envelope hypothesis.
University of Maryland
The discovery of novel vascular endothelial growth factor receptor tyrosine kinases inhibitors: pharmacophore modeling, virtual screening and docking studies.
Shanghai Jiao Tong University
Alpha-noradrenergic receptor binding in mammalian brain: differential labeling of agonist and antagonist states.
TBA
Discovery of SCH446211 (SCH6): a new ketoamide inhibitor of the HCV NS3 serine protease and HCV subgenomic RNA replication.
Schering-Plough Research Institute