PMID

Data

Article Title

Organization

Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators.

Pfizer

Development of Novel Alkene Oxindole Derivatives As Orally Efficacious AMP-Activated Protein Kinase Activators.

Chinese Academy of Sciences

Discovery of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(tert-butyl)pyridine-3-sulfonamide (CZC24758), as a potent, orally bioavailable and selective inhibitor of PI3K for the treatment of inflammatory disease.

Cellzome

A quantitative analysis of kinase inhibitor selectivity.

Ambit Biosciences

Comprehensive analysis of kinase inhibitor selectivity.

Ambit Biosciences

AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML).

Ambit Biosciences

Synthesis and SAR of 4-substituted-2-aminopyrimidines as novel c-Jun N-terminal kinase (JNK) inhibitors.

Pfizer

Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitors.

University of Colorado Anschutz Medical Campus

Discovery of 4

TBA

Structure-based rational design of staurosporine-based fluorescent probe with broad-ranging kinase affinity for kinase panel application.

Takeda Pharmaceutical

 

CDK2 in CSAR_FULL_RELEASE_3JULY2012

Csar

Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells.

Johnson & Johnson Pharmaceutical