PMID

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Article Title

Organization

Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker.

Northwestern University

Selective Acetamidine-Based Nitric Oxide Synthase Inhibitors: Synthesis, Docking, and Biological Studies.

University of Chieti&Quot;G. D'Annunzio&Quot

2-Aminopyridines with a Truncated Side Chain To Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity.

Northwestern University

Novel 2,4-disubstituted pyrimidines as potent, selective, and cell-permeable inhibitors of neuronal nitric oxide synthase.

Northwestern University

Structure-based design of bacterial nitric oxide synthase inhibitors.

University of California

Combination of chiral linkers with thiophenecarboximidamide heads to improve the selectivity of inhibitors of neuronal nitric oxide synthase.

Northwestern University

Nitric oxide synthase inhibitors that interact with both heme propionate and tetrahydrobiopterin show high isoform selectivity.

Northwestern University

Simplified 2-aminoquinoline-based scaffold for potent and selective neuronal nitric oxide synthase inhibition.

Northwestern University

Potent and selective double-headed thiophene-2-carboximidamide inhibitors of neuronal nitric oxide synthase for the treatment of melanoma.

Northwestern University

An Accessible Chiral Linker to Enhance Potency and Selectivity of Neuronal Nitric Oxide Synthase Inhibitors.

Northwestern University

Chiral linkers to improve selectivity of double-headed neuronal nitric oxide synthase inhibitors.

Northwestern University

In search of potent and selective inhibitors of neuronal nitric oxide synthase with more simple structures.

Northwestern University

Effects of (-)-epicatechin and derivatives on nitric oxide mediated induction of mitochondrial proteins.

University of California

Cyclopropyl- and methyl-containing inhibitors of neuronal nitric oxide synthase.

University of California

Structure-guided design of selective inhibitors of neuronal nitric oxide synthase.

Northwestern University

Synthesis and evaluation of pyrido[1,2-a]pyrimidines as inhibitors of nitric oxide synthases.

Christian-Albrechts-University of Kiel

Potent and selective conformationally restricted neuronal nitric oxide synthase inhibitors.

Northwestern University

Aromatic reduced amide bond peptidomimetics as selective inhibitors of neuronal nitric oxide synthase.

Northwestern University

Computer modeling of selective regions in the active site of nitric oxide synthases: implication for the design of isoform-selective inhibitors.

Northwestern University

Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5-[aminoakyl]aminopentyl)-N'-nitroguanidines, potent and highly selective inhibitors of neuronal nitric oxide synthase.

Northwestern University

Synthesis and evaluation of peptidomimetics as selective inhibitors and active site probes of nitric oxide synthases.

Northwestern University

N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase.

Northwestern University

Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine.

Northwestern University

Selective inhibition of neuronal nitric oxide synthase by N omega-nitroarginine-and phenylalanine-containing dipeptides and dipeptide esters.

Northwestern University

Approaches toward selective inhibition of nitric oxide synthase.

University of Michigan

Novel inhibitors of neuronal nitric oxide synthase with potent antioxidant properties.

Institut Henri Beaufour

1H-pyrazole-1-carboxamidines: new inhibitors of nitric oxide synthase.

Northwestern University

Intramolecular hydrogen bonding: a potential strategy for more bioavailable inhibitors of neuronal nitric oxide synthase.

Northwestern University

Improved synthesis of chiral pyrrolidine inhibitors and their binding properties to neuronal nitric oxide synthase.

Northwestern University

Symmetric double-headed aminopyridines, a novel strategy for potent and membrane-permeable inhibitors of neuronal nitric oxide synthase.

Northwestern University

Exploration of the active site of neuronal nitric oxide synthase by the design and synthesis of pyrrolidinomethyl 2-aminopyridine derivatives.

Northwestern University

N-Substituted acetamidines and 2-methylimidazole derivatives as selective inhibitors of neuronal nitric oxide synthase.

Università

Peripheral but crucial: a hydrophobic pocket (Tyr(706), Leu(337), and Met(336)) for potent and selective inhibition of neuronal nitric oxide synthase.

Northwestern University

Structure-based design, synthesis, and biological evaluation of lipophilic-tailed monocationic inhibitors of neuronal nitric oxide synthase.

Northwestern University

Potent and selective neuronal nitric oxide synthase inhibitors with improved cellular permeability.

Northwestern University

Analogues of 2-aminopyridine-based selective inhibitors of neuronal nitric oxide synthase with increased bioavailability.

Northwestern University

Discovery of highly potent and selective inhibitors of neuronal nitric oxide synthase by fragment hopping.

Northwestern University

Inhibitory effects of a series of 7-substituted-indazoles toward nitric oxide synthases: particular potency of 1H-indazole-7-carbonitrile.

Université

Selective L-nitroargininylaminopyrrolidine and L-nitroargininylaminopiperidine neuronal nitric oxide synthase inhibitors.

Northwestern University

Conformationally restricted dipeptide amides as potent and selective neuronal nitric oxide synthase inhibitors.

Northwestern University

Guanidine-substituted imidazoles as inhibitors of nitric oxide synthase.

Wake Forest University Winston-Salem

Nitroaromatic amino acids as inhibitors of neuronal nitric oxide synthase.

Abbott Laboratories

Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase.

Northwestern University

Discovery of N-{3-[(ethanimidoylamino)methyl]benzyl}-l-prolinamide dihydrochloride: A new potent and selective inhibitor of the inducible nitric oxide synthase as a promising agent for the therapy of malignant glioma.

University of Chieti "G. D'Annunzio

Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors.

Northwestern University

2-(2-indolyl-)-4(3H)-quinazolines derivates as new inhibitors of AChE: design, synthesis, biological evaluation and molecular modelling.

Sun Yat-Sen University

Identification and characterization of novel somatostatin antagonists.

Cyenamid Agricultural Research Center

Alkyl-CoA disulfides as inhibitors and mechanistic probes for FabH enzymes.

Portland State University

Covalent reactions of wortmannin under physiological conditions.

Massachusetts General Hospital