20 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Synthesis and evaluation of¿-lactam analogs of PGE2 as EP4 and EP2/EP4 agonists.
Minase Research Institute
Discovery of new chemical leads for prostaglandin D2 receptor antagonists.
Minase Research Institute
Discovery of novel prostaglandin analogs as potent and selective EP2/EP4 dual agonists.
Minase Research Institute
Discovery of a novel EP2/EP4 dual agonist with high subtype-selectivity.
Minase Research Institute
Synthesis and evaluation of novel modified¿-lactam prostanoids as EP4 subtype-selective agonists.
Minase Research Institute
Design and synthesis of new prostaglandin D2 receptor antagonists.
Minase Research Institute
Discovery of selective indole-based prostaglandin D2 receptor antagonist.
Minase Research Institute
3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 3: Synthesis, metabolic stability, and biological evaluation of optically active analogs.
Minase Research Institute
Discovery of novel N-acylsulfonamide analogs as potent and selective EP3 receptor antagonists.
Minase Research Institute
3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 1: discovery and exploration of the carboxyamide side chain.
Minase Research Institute
3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. part 2: optimization of the side chains to improve in vitro and in vivo potencies.
Minase Research Institute
Structure-activity relationship studies leading to the identification of (2E)-3-[l-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methyl-lH-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide (DG-041), a potent and selective prostanoid EP3 receptor antagonist, as a novel antiplatelet agent that
Decode Chemistry
3,4-Disubstituted indole acylsulfonamides: a novel series of potent and selective human EP3 receptor antagonists.
Decode Chemistry
Discovery of orally active prostaglandin D2 receptor antagonists.
Minase Research Institute
Design and synthesis of a highly selective EP4-receptor agonist. Part 2: 5-thia and 9beta-haloPG derivatives with improved stability.
Minase Research Institute
Design and synthesis of a highly selective EP4-receptor agonist. Part 1: 3,7-dithiaPG derivatives with high selectivity.
Minase Research Institute
Design and synthesis of a highly selective EP2-receptor agonist.
Minase Research Institute