PMID

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Article Title

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Development of an in vivo active, dual EP1 and EP3 selective antagonist based on a novel acyl sulfonamide bioisostere.

Vanderbilt University School of Medicine

Synthesis and evaluation of¿-lactam analogs of PGE2 as EP4 and EP2/EP4 agonists.

Minase Research Institute

Discovery of new chemical leads for prostaglandin D2 receptor antagonists.

Minase Research Institute

Discovery of novel prostaglandin analogs as potent and selective EP2/EP4 dual agonists.

Minase Research Institute

Discovery of a novel EP2/EP4 dual agonist with high subtype-selectivity.

Minase Research Institute

Synthesis and evaluation of novel modified¿-lactam prostanoids as EP4 subtype-selective agonists.

Minase Research Institute

Design and synthesis of new prostaglandin D2 receptor antagonists.

Minase Research Institute

Discovery of selective indole-based prostaglandin D2 receptor antagonist.

Minase Research Institute

3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 3: Synthesis, metabolic stability, and biological evaluation of optically active analogs.

Minase Research Institute

Discovery of novel N-acylsulfonamide analogs as potent and selective EP3 receptor antagonists.

Minase Research Institute

3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 1: discovery and exploration of the carboxyamide side chain.

Minase Research Institute

3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. part 2: optimization of the side chains to improve in vitro and in vivo potencies.

Minase Research Institute

Discovery of orally active prostaglandin D2 receptor antagonists.

Minase Research Institute

Design and synthesis of a highly selective EP4-receptor agonist. Part 2: 5-thia and 9beta-haloPG derivatives with improved stability.

Minase Research Institute

Design and synthesis of a highly selective EP4-receptor agonist. Part 1: 3,7-dithiaPG derivatives with high selectivity.

Minase Research Institute

Design and synthesis of a highly selective EP2-receptor agonist.

Minase Research Institute

Salvinorin A: a potent naturally occurring nonnitrogenous kappa opioid selective agonist.

Case Western Reserve University