PMID

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Article Title

Organization

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 3.

Nippon Roche Research Center

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 2.

Nippon Roche Research Center

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 1.

Nippon Roche Research Center

Discovery of high affinity inhibitors of Leishmania donovani N-myristoyltransferase.

Imperial College

Discovery of pyridyl-based inhibitors of Plasmodium falciparum N-myristoyltransferase.

Imperial College

Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-myristoyltransferase inhibitors: identification and evaluation of CNS penetrant compounds as potential treatments for stage 2 human African trypanosomiasis.

University of Dundee

Structure-based design of potent and selective Leishmania N-myristoyltransferase inhibitors.

Imperial College

Discovery of novel and ligand-efficient inhibitors of Plasmodium falciparum and Plasmodium vivax N-myristoyltransferase.

Imperial College

Design and synthesis of inhibitors of Plasmodium falciparum N-myristoyltransferase, a promising target for antimalarial drug discovery.

Imperial College

Discovery of Plasmodium vivax N-myristoyltransferase inhibitors: screening, synthesis, and structural characterization of their binding mode.

Imperial College

Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors.

University of Dundee

Derivatives of aryl amines containing the cytotoxic 1,4-dioxo-2-butenyl pharmacophore.

Acadia University

 

A chiral recognition element with an unusual size constraint affects the potency and selectivity for peptidomimetic inhibitors of Candida albicans myristoyl-CoA:protein N-myristoyltransferase

TBA

Fragment Linking Strategies for Structure-Based Drug Design.

Universit£

Novel Thienopyrimidine Inhibitors of

Imperial College London

Fragment-to-Lead Medicinal Chemistry Publications in 2018.

Frontier Medicines

How To Design Selective Ligands for Highly Conserved Binding Sites: A Case Study Using

Johannes Gutenberg-Universit£T Mainz

Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity.

G.D. Searle

Design and syntheses of potent and selective dipeptide inhibitors of Candida albicans myristoyl-CoA:protein N-myristoyltransferase.

G.D. Searle And

A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors.

University of Dundee

Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase Inhibitors.

University of Dundee