PMID

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Article Title

Organization

The discovery of 4-{1-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoic acid (MK-2894), a potent and selective prostaglandin E2 subtype 4 receptor antagonist.

Merck Frosst Centre For Therapeutic Research

Discovery of GSK345931A: An EP(1) receptor antagonist with efficacy in preclinical models of inflammatory pain.

Glaxosmithkline

2,3-Diarylthiophenes as selective EP1 receptor antagonists.

Merck Frosst Centre For Therapeutic Research

Discovery of novel pyrazolo[1,5-a]pyridine-based EP

Kyorin Pharmaceutical

Identification of novel 1,2,3,6-tetrahydropyridyl-substituted benzo[d]thiazoles: Lead generation and optimization toward potent and orally active EP

Kyorin Pharmaceutical

Novel pyrazolo[1,5-a]pyridines as orally active EP

Kyorin Pharmaceutical

Synthesis of new 8(S)-HETE analogs and their biological evaluation as activators of the PPAR nuclear receptors.

Universit?? De Rennes 1