19 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
Organization
Identification of Potential Off-target Toxicity Liabilities of Catechol-O-methyltransferase Inhibitors by Differential Competition Capture Compound Mass Spectrometry.
Caprotec Bioanalytics
Synthesis and optimization of N-heterocyclic pyridinones as catechol-O-methyltransferase (COMT) inhibitors.
Merck
Potency and inactivation rates of analogues of an irreversible inhibitor of vertebrate oxidosqualene cyclase
TBA
2,3:18,19-dioxidosqualene: synthesis and activity as a potent inhibitor of 2,3-oxidosqualene-lanosterol cyclase in rat liver microsomes
TBA
Design of Potent and Druglike Nonphenolic Inhibitors for Catechol O-Methyltransferase Derived from a Fragment Screening Approach Targeting the S-Adenosyl-l-methionine Pocket.
F. Hoffmann-La Roche
Novel 4-piperidinopyridine inhibitors of oxidosqualene cyclase-lanosterol synthase derived by consideration of inhibitor pK(a).
Astrazeneca
Evaluation of nitrocatechol chalcone and pyrazoline derivatives as inhibitors of catechol-O-methyltransferase and monoamine oxidase.
North-West University
A novel series of 4-piperidinopyridine and 4-piperidinopyrimidine inhibitors of 2,3-oxidosqualene cyclase-lanosterol synthase.
Astrazeneca
Synthesis and Evaluation of Bicyclic Hydroxypyridones as Inhibitors of Catechol
Lieber Institute For Brain Development
Quinuclidine inhibitors of 2,3-oxidosqualene cyclase-lanosterol synthase: optimization from lipid profiles.
Zeneca Pharmaceuticals
29-Methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase.
Università
Synthesis and inhibition studies of sulfur-substituted squalene oxide analogues as mechanism-based inhibitors of 2,3-oxidosqualene-lanosterol cyclase.
Simon Fraser University
Structural and stereoelectronic requirements for the inhibition of mammalian 2,3-oxidosqualene cyclase by substituted isoquinoline derivatives.
Laboratoires Fournier
Optimization of 8-Hydroxyquinolines as Inhibitors of Catechol O-Methyltransferase.
Lieber Institute For Brain Development
Squalene analogues containing isopropylidene mimics as potential inhibitors of pig liver squalene epoxidase and oxidosqualene cyclase.
State University of New York