PMID

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Article Title

Organization

Structure-activity relationship study of 4EGI-1, small molecule eIF4E/eIF4G protein-protein interaction inhibitors.

Harvard Medical School

Synthesis of rigidified eIF4E/eIF4G inhibitor-1 (4EGI-1) mimetic and their in vitro characterization as inhibitors of protein-protein interaction.

Harvard Medical School

Structure-guided design, synthesis, and evaluation of guanine-derived inhibitors of the eIF4E mRNA-cap interaction.

Amgen

Synthesis and evaluation of potential inhibitors of eIF4E cap binding to 7-methyl GTP.

University of Minnesota

A collection of caged compounds for probing roles of local translation in neurobiology.

University of Toronto

Update on the Development of MNK Inhibitors as Therapeutic Agents.

A*Star

Progress in developing MNK inhibitors.

Ocean University of China and Laboratory For Marine Drugs and Bioproducts

A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders.

Dana-Farber Cancer Institute

A cell-penetrant lactam-stapled peptide for targeting eIF4E protein-protein interactions.

University of Michigan

Consideration of Binding Kinetics in the Design of Stapled Peptide Mimics of the Disordered Proteins Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 and Eukaryotic Translation Initiation Factor 4G.

University of Michigan

7-Methylguanosine monophosphate analogues with 5'-(1,2,3-triazoyl) moiety: Synthesis and evaluation as the inhibitors of cNIIIB nucleotidase.

University of Warsaw

Anchimerically Activated ProTides as Inhibitors of Cap-Dependent Translation and Inducers of Chemosensitization in Mantle Cell Lymphoma.

Mayo Clinic