PMID

Data

Article Title

Organization

Dual-Specificity Phosphatase CDC25A/B Inhibitor Identified from a Focused Library with Nonelectrophilic Core Structure.

TBA

Arylstibonic acids are potent and isoform-selective inhibitors of Cdc25a and Cdc25b phosphatases.

Imperial College

Synthesis of small molecule CDC25 phosphatases inhibitors.

Institut Henri Beaufour

Syntheses and biological activities of a novel group of steroidal derived inhibitors for human Cdc25A protein phosphatase.

Georgia Institute of Technology

Using small molecules to target protein phosphatases.

Max Planck Institute of Molecular Physiology

Synthesis and biological evaluation of novel coumarin-based inhibitors of Cdc25 phosphatases.

Université

Synthesis and biological evaluation of dialkylsubstituted maleic anhydrides as novel inhibitors of Cdc25 dual specificity phosphatases.

Université

PTP-1B inhibitors: cyclopenta[d][1,2]-oxazine derivatives.

Korea Research Institute of Chemical Technology

Synthesis and biological evaluation of novel heterocyclic quinones as inhibitors of the dual specificity protein phosphatase CDC25C.

Institut Henri Beaufour

Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors.

Abbott Laboratories

Selective protein tyrosine phosphatase 1B inhibitors: targeting the second phosphotyrosine binding site with non-carboxylic acid-containing ligands.

Abbott Laboratories

Inhibition of Cdc25 phosphatases by indolyldihydroxyquinones.

Duke University

Dysidiolide and related gamma-hydroxy butenolide compounds as inhibitors of the protein tyrosine phosphatase, CDC25.

Mitotix

Identification of highly potent and selective Cdc25 protein phosphatases inhibitors from miniaturization click-chemistry-based combinatorial libraries.

Shandong University

Discovery of Novel Naphthylphenylketone and Naphthylphenylamine Derivatives as Cell Division Cycle 25B (CDC25B) Phosphatase Inhibitors: Design, Synthesis, Inhibition Mechanism, and in Vitro Efficacy against Melanoma Cell Lines.

University of Naples Federico Ii

Novel coumarin- and quinolinone-based polycycles as cell division cycle 25-A and -C phosphatases inhibitors induce proliferation arrest and apoptosis in cancer cells.

Sapienza University of Rome