PMID

Data

Article Title

Organization

Derivatives of dibenzothiophene for positron emission tomography imaging ofa7-nicotinic acetylcholine receptors.

The Johns Hopkins University School of Medicine

Characterization of a novela-conotoxin TxID from Conus textile that potently blocks rata3ß4 nicotinic acetylcholine receptors.

Hainan University

From a4ß2 Nicotinic Ligands to the Discovery of s1 Receptor Ligands: Pharmacophore Analysis and Rational Design.

TBA

Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations.

The Danish University of Pharmaceutical Sciences

SAR ofa7 nicotinic receptor agonists derived from tilorone: exploration of a novel nicotinic pharmacophore.

Abbott Laboratories

Novel N-methylated 8-oxoisoguanines from Pacific sponges with diverse neuroactivities.

Hokkaido University

 

Identification of novel (isoxazole)methylene-1-azabicyclic compounds with high affinity for the central nicotinic cholinergic receptor

TBA

Selective Penicillamine Substitution Enables Development of a Potent Analgesic Peptide that Acts through a Non-Opioid-Based Mechanism.

University of Utah

Mechanism of Action and Structure-Activity Relationship of ?-Conotoxin Mr1.1 at the Human ?9?10 Nicotinic Acetylcholine Receptor.

Ocean University of China

Novel pyridyl ring C5 substituted analogues of epibatidine and 3-(1-methyl-2(S)-pyrrolidinylmethoxy)pyridine (A-84543) as highly selective agents for neuronal nicotinic acetylcholine receptors containing beta2 subunits.

University of Illinois At Chicago

Discovery of Methylene Thioacetal-Incorporated ?-RgIA Analogues as Potent and Stable Antagonists of the Human ?9?10 Nicotinic Acetylcholine Receptor for the Treatment of Neuropathic Pain.

University of Utah

Synthesis and nicotinic binding of novel phenyl derivatives of UB-165. Identifying factors associated with alpha7 selectivity.

University of Bristol

Computational and Functional Mapping of Human and Rat ?6?4 Nicotinic Acetylcholine Receptors Reveals Species-Specific Ligand-Binding Motifs.

Veterans Affairs Medical Center

New Rigid Nicotine Analogues, Carrying a Norbornane Moiety, Are Potent Agonists of ?7 and ?3* Nicotinic Receptors.

University of Florence

Structural basis for alpha-conotoxin potency and selectivity.

Boise State University