BDBM50002096 ALO-4943A::CHEMBL1719::KW-4679::OLOPATADINE HYDROCHLORIDE::Olopatadine::Pataday::Patanol::[11-(3-Dimethylamino-propylidene)-6,11-dihydro-dibenzo[b,e]oxepin-2-yl]-acetic acid; hydrochloride

SMILES CN(C)CC\C=C1\c2ccccc2COc2ccc(CC(O)=O)cc12

InChI Key InChIKey=JBIMVDZLSHOPLA-UHFFFAOYSA-N

Data  1 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50002096   

TargetHistamine H1 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50002096BDBM50002096(KW-4679 | ALO-4943A | Pataday | [11-(3-Dimethylami...)
Affinity DataKd:  0.00600nMAssay Description:Displacement of [3H]-mepyramine from human histamine H1 receptor expressed in HEK293T cells assessed as dissociation rate constant (Koff) incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistamine H1 receptor(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50002096BDBM50002096(KW-4679 | ALO-4943A | Pataday | [11-(3-Dimethylami...)
Affinity DataKi:  16nMAssay Description:The compound was tested in vitro for binding affinity against histamine H1 receptor from guinea pig cerebellum, using [3H]pyrilamine as radioligand a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed