BDBM259409 US10457647, Example 8::US11180460, Example 8::US11673868, Example 8::US9512084, 8

SMILES CN(CCOc1c(N)ncnc1-c1cc(F)cc(NC(=O)c2ccc(cc2F)C2CC2)c1C)C(=O)C#C

InChI Key InChIKey=XYWKJTSMMUJKFG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 259409   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM259409(US10457647, Example 8 | US11180460, Example 8 | US...)
Affinity DataIC50:  2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent