BDBM50012957 1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea::1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea::5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide::5-chloro-N-(2-{4-[N-(N-cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide::CHEMBL472::GLYBURIDE::Glibenclamide::US20230348371, Compound 5

SMILES COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1

InChI Key InChIKey=ZNNLBTZKUZBEKO-UHFFFAOYSA-N

Data  8 KI  36 IC50  2 EC50

PDB links: 14 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50012957   

TargetSurfeit locus protein 1(Human)
Shanghai Senhui Medicine

US Patent
LigandPNGBDBM50012957(1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfon...)
Affinity DataIC50:  6nMAssay Description:Procedures:a) 100 μL of reaction buffer was added to each well of a 96-well deep-well plate.b) 5 μL of diluted test compound (1% DMSO) was ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSurfeit locus protein 1(Human)
Shanghai Senhui Medicine

US Patent
LigandPNGBDBM50012957(1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfon...)
Affinity DataIC50:  9nMAssay Description:Procedures:a) 100 μL of reaction buffer was added to each well of a 96-well deep-well plate.b) 5 μL of diluted test compound (1% DMSO) was ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSurfeit locus protein 1(Human)
Shanghai Senhui Medicine

US Patent
LigandPNGBDBM50012957(1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfon...)
Affinity DataIC50:  9nMAssay Description:Procedures:a) 100 μL of reaction buffer was added to each well of a 96-well deep-well plate.b) 5 μL of diluted test compound (1% DMSO) was ...More data for this Ligand-Target Pair
In DepthDetails US Patent