BDBM283235 4-{2-(4-aminopiperidyl)-1-methyl- 6-oxo-5-[6-(trifluoromethyl) (3- pyridyl)]hydropyrimidin-4-yl}- 2-fluorobenzenecarbonitrile::US10023543, Example 23::US10207999, Example 23::US10328077, Example 23::US10548896, Example 23::US10849898, Example 23::US10960005, Example 23::US11084793, Example 23::US9573930, Example 23::US9771329, Example 23::US9776974, Example 23
SMILES Cn1c(nc(-c2ccc(C#N)c(F)c2)c(-c2ccc(nc2)C(F)(F)F)c1=O)N1CCC(N)CC1
InChI Key InChIKey=ACMNUSISKUJCSP-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 283235
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair