BDBM127724 US10251889, Example 97::US10758542, Example 97::US8791123, 97::US9782415, Example 97::US9796724, Example 97

SMILES FC(CCl)CNC(=O)c1cnn2ccc(nc12)N1CCC[C@@H]1c1cncc(F)c1

InChI Key InChIKey=QHRTXUATNCWBBL-BZSJEYESSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 127724   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharm

US Patent
LigandPNGBDBM127724(US10251889, Example 97 | US10758542, Example 97 | ...)
Affinity DataIC50: >1.00E+3nMAssay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Array Biopharm

US Patent
LigandPNGBDBM127724(US10251889, Example 97 | US10758542, Example 97 | ...)
Affinity DataIC50:  6.20nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In DepthDetails US Patent