BDBM32657 benzamidine- based compound, 6
SMILES N[C@H](C(c1ccccc1)c1ccccc1)C(=O)N1CCCC1C(=O)NCc1ccc(cc1)C(N)=N
InChI Key InChIKey=ODAPDZPYLPTJOD-XSWBTSGESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 32657
Affinity DataKi: 0.100nM ΔG°: -13.6kcal/molepH: 7.4 T: 2°CAssay Description:Kinetic inhibition of human thrombin was determined photometrically at 405 nm using the chromogenic substrate Pefachrom tPa. Reactions were performed...More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 4 hits for monomerid = 32657
ITC DataΔG°: -11.6kcal/mole −TΔS°: -0.214kcal/mole ΔH°: -11.3kcal/mole
pH: 7.8 T: 25.00°C
pH: 7.8 T: 25.00°C
ITC DataΔG°: -11.3kcal/mole −TΔS°: -0.812kcal/mole ΔH°: -10.5kcal/mole
pH: 7.8 T: 25.00°C
pH: 7.8 T: 25.00°C
ITC DataΔG°: -12.5kcal/mole −TΔS°: -1.64kcal/mole ΔH°: -10.8kcal/mole
pH: 7.8 T: 25.00°C
pH: 7.8 T: 25.00°C
ITC DataΔG°: -11.1kcal/mole −TΔS°: -1.36kcal/mole ΔH°: -9.74kcal/mole
pH: 7.8 T: 25.00°C
pH: 7.8 T: 25.00°C