BDBM35362 5-bromanyl-N-(3-cyano-1-phenyl-pyrrolo[3,2-b]quinoxalin-2-yl)furan-2-carboxamide::5-bromo-N-(3-cyano-1-phenyl-2-pyrrolo[3,2-b]quinoxalinyl)-2-furancarboxamide::5-bromo-N-(3-cyano-1-phenyl-pyrrolo[3,2-b]quinoxalin-2-yl)-2-furamide::5-bromo-N-(3-cyano-1-phenylpyrrolo[3,2-b]quinoxalin-2-yl)furan-2-carboxamide::MLS000068756::SMR000039905::cid_658921

SMILES Brc1ccc(o1)C(=O)Nc1c(C#N)c2nc3ccccc3nc2n1-c1ccccc1

InChI Key InChIKey=NGFYSVJWYNOJNU-UHFFFAOYSA-N

Data  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 35362   

TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35362(5-bromanyl-N-(3-cyano-1-phenyl-pyrrolo[3,2-b]quino...)
Affinity DataIC50:  1.40E+4nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35362(5-bromanyl-N-(3-cyano-1-phenyl-pyrrolo[3,2-b]quino...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35362(5-bromanyl-N-(3-cyano-1-phenyl-pyrrolo[3,2-b]quino...)
Affinity DataIC50:  2.44E+4nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35362(5-bromanyl-N-(3-cyano-1-phenyl-pyrrolo[3,2-b]quino...)
Affinity DataIC50:  7.02E+3nMAssay Description:The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screenin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35362(5-bromanyl-N-(3-cyano-1-phenyl-pyrrolo[3,2-b]quino...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-3 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-3...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35362(5-bromanyl-N-(3-cyano-1-phenyl-pyrrolo[3,2-b]quino...)
Affinity DataIC50:  1.55E+4nMAssay Description:The MKP-3 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-3 inhibit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35362(5-bromanyl-N-(3-cyano-1-phenyl-pyrrolo[3,2-b]quino...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay