BDBM50120421 CHEMBL2402206

SMILES Cc1ccc(c(C)c1)S(=O)(=O)c1cnc(SCC(=O)Nc2ccccc2C(F)(F)F)[nH]c1=O

InChI Key InChIKey=XHKKCXMZBGDTIT-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 Kd  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50120421   

TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50120421(CHEMBL2402206)
Affinity DataIC50:  1.18E+5nMAssay Description:Displacement of MR121-Nrf2 from human N-terminal His-tagged Kelch-DC domain of Keap1 (321 to 609) expressed in Escherichia coli BL21 (DE3) after 40 m...More data for this Ligand-Target Pair