BDBM21492 4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline::CHEMBL261454::LY364947::US11759530, Compound Table1.1::US9138393, LY-364947::US9144538, LY-364947

SMILES c1[nH]nc(c1-c1ccnc2ccccc12)-c1ccccn1

InChI Key InChIKey=IBCXZJCWDGCXQT-UHFFFAOYSA-N

Data  18 IC50  2 Kd  1 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21492   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL

LigandBDBM21492(4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline | CH...)Copy SMILESCopy InChI

Affinity DataIC50:  5.10E+4nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLDrugBankMCE
MMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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