BDBM50156495 8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-one::8-Dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one::8-dibenzothiophen-1-yl-2-morpholin-4-yl-chromen-4-one::CHEMBL188678::NU-7432::NU-7441

SMILES O=c1cc(oc2c(cccc12)-c1cccc2c3ccccc3sc12)N1CCOCC1

InChI Key InChIKey=JAMULYFATHSZJM-UHFFFAOYSA-N

Data  1 KI  26 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50156495   

TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156495(8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chro...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156495(8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chro...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156495(8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Ataxia telangiectasia related protein ATR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156495(8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chro...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Mammalian target of Rapamycin mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156495(8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chro...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Phosphatidylinositol 3-kinase p110 alpha subunitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156495(8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Mutated in ataxia telangiectasia protein ATM kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed