BDBM17662 (2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl)propanoic acid::2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid::AMPA::CHEMBL276815

SMILES Cc1o[nH]c(=O)c1C[C@H](N)C(O)=O

InChI Key InChIKey=UUDAMDVQRQNNHZ-YFKPBYRVSA-N

Data  17 KI  2 IC50  5 EC50

PDB links: 8 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 17662   

TargetGlutamate receptor 2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM17662((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...)
Affinity DataKi:  16.8nMAssay Description:Binding affinity for ionotropic Glutamate receptor AMPA 2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 3(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM17662((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...)
Affinity DataKi:  20.6nMAssay Description:Binding affinity for ionotropic Glutamate receptor AMPA 3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM17662((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...)
Affinity DataKi:  21.9nMAssay Description:Binding affinity for ionotropic Glutamate receptor AMPA 1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 4(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM17662((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...)
Affinity DataKi:  40nMAssay Description:Binding affinity for ionotropic Glutamate receptor AMPA 4 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM17662((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...)
Affinity DataKi:  1.15E+3nMAssay Description:Binding affinity for kainate Glutamate receptor GluR5 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM17662((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...)
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity for kainate Glutamate receptor GluR6 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM17662((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...)
Affinity DataEC50:  3.80E+3nMAssay Description:In vitro activity of the compound at Ionotropic glutamate receptor using cortical wedge assays in rat brain synaptosomaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed